Glutathione 1500mg – Direct from Shanghai Manufacturer
Glutathione (GSH) stands as one of the most critical molecules in cellular biology—the body’s master antioxidant, primary detoxifier, and essential regulator of redox homeostasis. This tripeptide, composed of glutamate, cysteine, and glycine, is synthesized within every cell and serves as the first line of defense against oxidative stress . If you are searching for “glutathione peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this essential tripeptide and can deliver the purity and stability your studies demand. That partner is Apeptide (Shanghai) Co., Ltd.
We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptides, amino acids, and biochemicals. When you purchase glutathione 1500mg from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller. glutathione peptide for sale
Understanding Glutathione: The Master Antioxidant
Glutathione (γ-L-glutamyl-L-cysteinylglycine) is a tripeptide found in virtually every cell of the human body . It is the most abundant intracellular thiol (sulfur-containing) antioxidant, with concentrations in the millimolar range in many tissues .
Key Characteristics
| Parameter | Specification |
|---|---|
| Sequence | γ-Glu-Cys-Gly |
| Molecular Formula | C₁₀H₁₇N₃O₆S |
| Molecular Weight | 307.32 g/mol |
| CAS Number | 70-18-8 |
| Form | Lyophilized powder |
| Purity | ≥99% (verified by HPLC) |
| Storage | -20°C, protected from light and moisture |
The Two Forms: Reduced vs. Oxidized
| Form | Abbreviation | Function | Research Significance |
|---|---|---|---|
| Reduced Glutathione | GSH | Active antioxidant; donates electrons to neutralize free radicals | Measures cellular antioxidant capacity |
| Oxidized Glutathione | GSSG | Inactive form formed when two GSH molecules donate electrons | Used as marker of oxidative stress (GSSG:GSH ratio) |
Mechanism of Action: The Antioxidant Cascade
| Function | Mechanism | Research Implications |
|---|---|---|
| Direct Free Radical Scavenging | Sulfhydryl (-SH) group donates electrons to neutralize ROS and RNS | Oxidative stress models, redox biology |
| Regeneration of Other Antioxidants | Recycles vitamins C and E back to their active forms | Antioxidant network studies |
| Detoxification | Conjugates with xenobiotics via glutathione S-transferase (GST) | Toxicology, drug metabolism |
| Cofactor for Enzymes | Essential for glutathione peroxidase, glutathione reductase, and GST | Enzyme activity studies |
| Mitochondrial Protection | Maintains mitochondrial membrane potential and prevents apoptosis | Mitochondrial dysfunction, cell death |
Why Glutathione Matters in Research
Glutathione is the subject of over 100,000 published studies, making it one of the most extensively researched molecules in biomedical science . Its central role in oxidative stress, detoxification, and cellular health makes it a critical research tool across multiple domains. glutathione peptide for sale
Key Research Applications
| Research Area | Key Findings | Research Context |
|---|---|---|
| Oxidative Stress | GSH depletion is a hallmark of oxidative stress; GSH/GSSG ratio indicates redox status | Aging, inflammation, neurodegeneration, cardiovascular disease |
| Detoxification & Toxicology | GSH conjugation is the primary pathway for eliminating xenobiotics; depletion increases susceptibility to toxins | Drug metabolism, environmental toxicology, chemotherapy resistance |
| Neurodegenerative Diseases | GSH levels are significantly reduced in Alzheimer’s, Parkinson’s, and Huntington’s diseases | Neuroprotection, disease mechanisms |
| Cardiovascular Research | Low GSH correlates with cardiovascular risk; supplementation improves endothelial function | Heart disease, atherosclerosis, ischemia-reperfusion injury |
| Immunology | GSH supports lymphocyte proliferation and function; depletion impairs immune response | Immunosenescence, autoimmune disease |
| Liver Health | GSH is the primary antioxidant in hepatocytes; depletion contributes to NAFLD and cirrhosis | Hepatology, fatty liver disease |
| Aging Research | GSH levels decline with age; associated with age-related functional decline | Gerontology, longevity studies |
| Mitochondrial Research | GSH protects mitochondria from oxidative damage; essential for mitochondrial function | Bioenergetics, cell metabolism |
Key Research Insights
| Finding | Significance |
|---|---|
| Rate-Limiting Cysteine | Cysteine availability is the rate-limiting factor for GSH synthesis; dietary cysteine (from N-acetylcysteine) is often used to boost GSH levels |
| Depletion Marker | GSH depletion is one of the earliest indicators of cellular stress and toxicity |
| Therapeutic Target | GSH elevation is a therapeutic strategy in numerous disease models |
| Stability Challenge | GSH is highly susceptible to oxidation, requiring careful handling and storage |
The Critical Importance of Quality for Glutathione Research
When you purchase glutathione peptide for sale, quality parameters are non-negotiable. Glutathione is highly susceptible to oxidation, and impurities can significantly affect experimental outcomes.
The Apeptide Quality Standard
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≥99% Purity Guarantee: Verified by High-Performance Liquid Chromatography (HPLC)
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Reduced Form Confirmation: Verified as reduced glutathione (GSH), not oxidized (GSSG)
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Mass Spectrometry: Molecular weight confirmation (307.32 g/mol expected)
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Amino Acid Analysis: Sequence verification (Glu-Cys-Gly)
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Heavy Metals: ≤10 ppm
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Residual Solvents: Meets ICH guidelines
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Water Content: ≤5.0% by Karl Fischer
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Endotoxin Testing: <0.05 EU/mg available for cell culture applications
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Batch-Specific COAs: Full traceability with Certificates of Analysis
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Stability Testing: Ensuring integrity from our lab to yours
Why Purity Matters for Glutathione Research
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Oxidative Stress Assays: GSSG contamination skews GSH/GSSG ratio measurements
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Cell Culture Applications: Impurities affect cell viability and redox status
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Enzyme Activity Studies: GST, GPx, and GR assays require pure substrate
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In Vivo Studies: Dosing consistency critical for reproducible results
The Manufacturer Advantage: Why Source Glutathione from Apeptide
When you search for “glutathione peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice. glutathione peptide for sale
Complete Transparency
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Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.
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Manufacturing Expertise: Decades of combined experience in peptide synthesis and biochemical production.
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No Middlemen: You pay manufacturer-direct pricing, not reseller markups.
Technical Expertise
Our team understands the specific requirements for glutathione research:
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Importance of reduced form (GSH) vs. oxidized form (GSSG)
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Proper handling to prevent oxidation
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Appropriate storage conditions (-20°C, desiccated)
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Documentation requirements for research compliance
Quality You Can Trust
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Rigorous Testing: Every batch undergoes HPLC, MS, and oxidation state analysis
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Documentation: Full COAs provided for complete traceability
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Consistency: Reliable quality batch after batch
Seamless Supply to the USA Market
Sourcing glutathione 1500mg from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners. glutathione peptide for sale
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Fast Shipping: 5-7 business days to US addresses
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Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive peptides
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Desiccant Protection: Double-sealed packaging to prevent moisture absorption
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Light Protection: Amber vials to prevent photodegradation
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Wholesale Programs: Dedicated support for small and large supply companies
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Customs Expertise: Smooth clearance with complete documentation
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Tracking Integration: Real-time visibility from Shanghai to your lab
Research Applications: Where Glutathione Excels
Understanding the diverse applications of glutathione helps researchers appreciate why quality matters.
Oxidative Stress Research
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Cellular redox state assessment
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Reactive oxygen species (ROS) quantification
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Lipid peroxidation (MDA, 4-HNE) studies
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Protein carbonylation and nitrosylation
Toxicology & Drug Development
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Hepatotoxicity models (acetaminophen, alcohol, chemotherapy)
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Heavy metal toxicity (lead, mercury, arsenic)
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Chemotherapeutic resistance studies
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Drug metabolism and detoxification pathways
Neurodegenerative Disease Research
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Alzheimer’s disease (amyloid-β toxicity)
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Parkinson’s disease (MPTP, 6-OHDA models)
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Huntington’s disease (mutant huntingtin)
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Stroke and ischemia-reperfusion injury
Cardiovascular Research
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Myocardial infarction and ischemia-reperfusion
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Endothelial dysfunction and atherosclerosis
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Hypertension and vascular redox status
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Diabetic cardiomyopathy
Immunology & Inflammation
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T-cell proliferation and activation
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Macrophage polarization and function
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Cytokine regulation and inflammatory signaling
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Autoimmune disease models
Aging & Longevity
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Cellular senescence markers
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Age-related mitochondrial decline
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Lifespan studies in model organisms
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Sarcopenia and muscle function
Liver Research
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Non-alcoholic fatty liver disease (NAFLD)
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Alcoholic liver disease (ALD)
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Hepatic fibrosis and cirrhosis
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Acetaminophen-induced hepatotoxicity
Frequently Asked Questions
: What exactly is glutathione peptide for sale at Apeptide?
A: Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. It is the body’s primary intracellular antioxidant and detoxifier. It is supplied strictly for laboratory investigation and research purposes, not for human consumption. Our product is the reduced (active) form with ≥99% purity. glutathione peptide for sale
: What purity levels do you guarantee for glutathione?
A: We guarantee ≥99% purity, verified by HPLC testing with Certificates of Analysis available for every batch. Each COA provides detailed purity analysis, mass spectrometry confirmation (307.32 g/mol expected), and batch-specific data.
: What is the CAS number for glutathione?
A: The CAS number for reduced glutathione (GSH) is 70-18-8 .
: What is the molecular weight of glutathione?
A: The molecular weight is 307.32 g/mol .
: What is the difference between reduced and oxidized glutathione?
A: Reduced glutathione (GSH) is the active antioxidant form with a free sulfhydryl group. Oxidized glutathione (GSSG) is formed when two GSH molecules donate electrons and form a disulfide bond. The GSH:GSSG ratio is a key indicator of cellular redox status .
: Why is glutathione called the “master antioxidant”?
A: Glutathione is the most abundant intracellular thiol antioxidant, directly neutralizes free radicals, and regenerates other antioxidants (vitamins C and E) back to their active forms, making it central to the entire antioxidant network .
: Is your glutathione for human consumption?
A: Absolutely not. Our glutathione is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. All products are labeled “FOR RESEARCH USE ONLY.”
: How should I store glutathione upon receipt?
A: Glutathione should be stored at -20°C (freezer) immediately upon receipt, protected from light and moisture. It is highly susceptible to oxidation and should be kept desiccated. Avoid repeated freeze-thaw cycles.
: What solvent should I use for reconstitution?
A: For most research applications, sterile water, PBS (pH 7.4), or cell culture medium is appropriate. Glutathione is soluble in aqueous buffers. For long-term storage, aliquot and store at -80°C. Contact our technical team for application-specific recommendations.
: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.
: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements.
: What documentation do you provide for research compliance?
A: Every order includes batch-specific Certificates of Analysis (COAs) with HPLC and MS data, confirming purity and reduced form status. We also provide commercial invoices, packing lists, and customs documentation as needed. glutathione peptide for sale
Quality Control: The Apeptide Standard
Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards.
Analytical Methods
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HPLC Analysis: Every batch tested for purity (≥99%)
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Mass Spectrometry: ESI-MS for molecular weight confirmation (307.32 Da expected)
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Amino Acid Analysis: Sequence verification (Glu-Cys-Gly)
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Reduced/Oxidized Form: Specific testing to confirm GSH vs. GSSG
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Heavy Metals: ≤10 ppm by ICP-MS
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Residual Solvents: Meets ICH Q3C guidelines
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Water Content: ≤5.0% by Karl Fischer
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Endotoxin Testing: <0.05 EU/mg available for cell culture applications
Batch Documentation
Each shipment includes:
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Certificate of Analysis with actual test results
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Confirmation of reduced form (GSH) status
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Batch number for traceability
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Expiration date and storage recommendations
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Reconstitution guidelines
Beyond Glutathione: A Complete Research Partner
Apeptide (Shanghai) Co., Ltd. is more than just a supplier of glutathione peptide for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide.
Our Capabilities
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Custom Synthesis: Develop proprietary peptides for your specific research needs
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Catalog Peptides: Hundreds of sequences available for immediate shipment
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Antioxidant Research Library: Including glutathione, N-acetylcysteine, and related compounds
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Fluorescent Dyes: High-purity labeling agents for imaging and detection
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Amino Acids: Building blocks for synthesis and research
Quality Certifications & Compliance
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Licensed manufacturer with physical facility in Pudong District, Shanghai
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Rigorous quality control protocols
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Transparent documentation and traceability
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Experienced technical support team
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Strict adherence to research-use-only compliance
The Science Behind Glutathione: The Master Antioxidant
Glutathione was first discovered in 1888 by J. de Rey-Pailhade, who identified a substance in yeast that could reduce elemental sulfur to hydrogen sulfide . Its structure was elucidated in 1929 by Hopkins and colleagues, establishing it as the tripeptide γ-glutamylcysteinylglycine . glutathione peptide for sale
The physiological importance of glutathione was established through decades of research demonstrating its essential role in:
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Redox homeostasis: Maintaining the balance between oxidants and antioxidants
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Thiol protection: Preserving protein thiol groups critical for enzyme function
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Detoxification: Conjugating with xenobiotics via glutathione S-transferase
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Immune function: Supporting lymphocyte proliferation and activity
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Mitochondrial integrity: Protecting mitochondrial DNA and membranes from oxidative damage
The synthesis of glutathione occurs in two ATP-dependent steps: (1) γ-glutamylcysteine formation by glutamate-cysteine ligase (GCL), the rate-limiting step; and (2) addition of glycine by glutathione synthetase (GS) . Cysteine availability is the primary limiting factor, making cysteine supplementation (via N-acetylcysteine) a common strategy to boost GSH levels . glutathione peptide for sale
Glutathione depletion is a hallmark of oxidative stress and is associated with numerous pathological conditions, including:
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Neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s)
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Cardiovascular diseases (atherosclerosis, heart failure)
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Metabolic disorders (diabetes, fatty liver disease)
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Aging and age-related decline
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Immune dysfunction
The GSH:GSSG ratio is considered one of the most reliable indicators of cellular redox status, making glutathione a critical endpoint in oxidative stress research.
The search for premium “glutathione peptide for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of peptides and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest research materials available. Whether you need glutathione for oxidative stress research, detoxification studies, or specialized investigations into cellular redox biology, we are your trusted manufacturing partner.












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