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Home / Peptides

Hexarelin Acetate

$80.00

Looking for hexarelin peptide for sale? Apeptide offers 99% pure research-grade hexarelin acetate.

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Hexarelin Acetate Peptide for Sale – Direct from Shanghai Manufacturer

Hexarelin stands as one of the most potent and extensively studied growth hormone secretagogues (GHS) in endocrinology research. This synthetic hexapeptide, also known as examorelin, was specifically designed to stimulate endogenous growth hormone (GH) release with remarkable potency and efficacy . If you are searching for “hexarelin peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this potent growth hormone secretagogue and can deliver the purity your studies demand. That partner is Apeptide (Shanghai) Co., Ltd.

We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase hexarelin acetate from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller.  hexarelin peptide for sale


Understanding Hexarelin: The Potent Growth Hormone Secretagogue

Hexarelin is a synthetic hexapeptide (6 amino acids) belonging to the growth hormone secretagogue (GHS) family. It was developed as one of the most potent GH-releasing peptides, with activity comparable to the natural hormone ghrelin .  hexarelin peptide for sale

Key Characteristics

Parameter Specification
Sequence H-His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH₂
Molecular Formula C₄₇H₅₈N₁₂O₆
Molecular Weight Approximately 887.04 g/mol
CAS Number 140703-51-1
Salt Form Acetate salt (enhanced stability and solubility)
Form Lyophilized powder
Purity ≥99% (verified by HPLC)
Storage -20°C, protected from light and moisture

Mechanism of Action: The Potent GH Secretagogue

Pathway Mechanism Research Implications
GHS-R1a Activation High-affinity binding to the ghrelin receptor (GHS-R1a) Growth hormone regulation, receptor pharmacology
GH Stimulation Potently stimulates endogenous growth hormone release Somatotroph function, GH pulsatility
Synergistic Effect Works synergistically with GHRH to amplify GH secretion Endocrine synergism, combinatorial signaling
Pituitary Action Direct action on pituitary somatotrophs Pituitary function, endocrine regulation
Hypothalamic Action Also acts on hypothalamic GHRH neurons Neuroendocrinology, central regulation

Why Hexarelin Matters in Research

Hexarelin is one of the most potent growth hormone secretagogues available for research, with an EC₅₀ in the low nanomolar range . Its high potency and well-characterized pharmacology have made it a valuable research tool for investigating the GH axis.

Key Research Applications

Research Area Key Findings Research Context
Growth Hormone Research One of the most potent GHS compounds; EC₅₀ in low nM range; induces robust GH release Endocrinology, pituitary function
Receptor Pharmacology High-affinity ligand for GHS-R1a; used to characterize ghrelin receptor pharmacology Receptor binding, drug development
Cardiovascular Research Cardioprotective effects independent of GH release; improves cardiac function in ischemia models Cardiovascular biology, cardioprotection
Metabolic Research Stimulates GH release; influences lipid metabolism and body composition Obesity, metabolic regulation
Endocrine Synergism Synergistic GH release with GHRH; used to study combinatorial signaling Neuroendocrinology, hormone interactions
Bone Metabolism Influences bone turnover markers via GH/IGF-1 axis Osteoporosis, bone biology

Potency Comparison

Compound GH Release Potency Selectivity Cardiovascular Effects
Hexarelin Highest Moderate Yes (independent of GH)
GHRP-6 High Low Minimal
Ipamorelin Moderate Highest Minimal
GHRH Moderate High No

The Critical Importance of Quality for Hexarelin Research

When you purchase hexarelin peptide for sale, quality parameters are non-negotiable. Hexarelin contains D-amino acids (D-2-Methyl-Trp, D-Phe) that require precise synthesis to ensure correct stereochemistry and full biological activity .  hexarelin peptide for sale

The Apeptide Quality Standard

  • 99% Purity Guarantee: Verified by High-Performance Liquid Chromatography (HPLC)

  • Mass Spectrometry: Molecular weight confirmation (887.04 g/mol expected)

  • Amino Acid Analysis: Sequence verification including D-amino acids

  • C-Terminal Amidation Confirmation: Essential for biological activity

  • Chiral Purity: Confirmation of D- and L-amino acid configurations

  • Peptide Content Determination: Accurate net peptide weight (≥80% typical)

  • Counterion Analysis: Acetate content specified

  • Water Content: ≤8.0% by Karl Fischer

  • Endotoxin Testing: <0.05 EU/mg available for cell culture applications

  • Batch-Specific COAs: Full traceability with Certificates of Analysis

  • Stability Testing: Ensuring integrity from our lab to yours

Why Purity Matters for Hexarelin Research

  • Receptor Binding Studies: EC₅₀ values in low nanomolar range require precise dosing

  • In Vivo Studies: Dosing consistency critical for GH and IGF-1 measurements

  • Cell Culture Applications: Impurities affect somatotroph viability

  • Mechanistic Studies: Pathway analysis demands documented purity


The Manufacturer Advantage: Why Source Hexarelin from Apeptide

When you search for “hexarelin peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice.  hexarelin peptide for sale

Complete Transparency

  • Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.

  • Manufacturing Expertise: Decades of combined experience in peptide synthesis including D-amino acids.

  • No Middlemen: You pay manufacturer-direct pricing, not reseller markups.

Technical Expertise

Our team understands the specific requirements for hexarelin research:

  • Importance of correct stereochemistry for receptor binding

  • Proper handling to maintain peptide stability

  • Appropriate reconstitution for various assay systems

  • Storage conditions to prevent degradation

  • Documentation requirements for research compliance

Quality You Can Trust

  • Rigorous Testing: Every batch undergoes HPLC and MS analysis

  • Documentation: Full COAs provided for complete traceability

  • Consistency: Reliable quality batch after batch


Seamless Supply to the USA Market

Sourcing hexarelin acetate from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners.  hexarelin peptide for sale

  • Fast Shipping: 5-7 business days to US addresses

  • Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive peptides

  • Desiccant Protection: Double-sealed packaging to prevent moisture absorption

  • Wholesale Programs: Dedicated support for small and large supply companies

  • Customs Expertise: Smooth clearance with complete documentation

  • Tracking Integration: Real-time visibility from Shanghai to your lab


Research Applications: Where Hexarelin Excels

Understanding the diverse applications of hexarelin helps researchers appreciate why quality matters.

Endocrinology Research

  • GH pulsatility and regulation studies

  • Pituitary somatotroph function

  • GHS-R1a receptor pharmacology

  • Comparative studies with other GHS compounds

  • Feedback mechanisms (IGF-1, somatostatin)

Receptor Pharmacology

  • High-affinity ligand binding studies

  • GHS-R1a signaling pathways

  • Biased agonism and arrestin recruitment

  • Structure-activity relationship investigations

Cardiovascular Research

  • Cardioprotection in ischemia-reperfusion models

  • Myocardial function and contractility

  • Endothelial function studies

  • Heart failure models

Metabolic Research

  • GH/IGF-1 axis and energy homeostasis

  • Lipid metabolism and body composition

  • Insulin sensitivity and glucose regulation

  • Adipose tissue biology

Bone & Muscle Biology

  • Osteoblast and osteoclast function

  • Muscle protein synthesis

  • Bone turnover markers

  • Sarcopenia models


Frequently Asked Questions

: What exactly is hexarelin acetate for sale at Apeptide?
A: Hexarelin (examorelin) is a synthetic hexapeptide (H-His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH₂) that acts as a potent growth hormone secretagogue by activating the ghrelin receptor (GHS-R1a). It is one of the most potent GH-releasing peptides available for research. It is supplied strictly for laboratory investigation and in vitro research only, not for human consumption. hexarelin peptide for sale

: What purity levels do you guarantee for hexarelin?
A: We guarantee 99% purity, verified by HPLC testing with Certificates of Analysis available for every batch. Each COA provides detailed purity analysis, mass spectrometry confirmation (887.04 g/mol expected), and batch-specific data.

: What is the CAS number for hexarelin?
A: The CAS number for hexarelin is 140703-51-1 .

: What is the molecular weight of hexarelin?
A: The molecular weight is approximately 887.04 g/mol .

: How does hexarelin differ from other growth hormone secretagogues?
A: Hexarelin is one of the most potent GHS compounds, with an EC₅₀ in the low nanomolar range. It also has unique cardioprotective effects that are independent of GH release, making it valuable for cardiovascular research .

: What is the primary mechanism of hexarelin?
A: Hexarelin activates the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons, stimulating robust growth hormone release. It also has direct cardioprotective effects mediated through the GHS-R1a receptor .  hexarelin peptide for sale

: Is your hexarelin for human consumption?
A: Absolutely not. Our hexarelin is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. All products are labeled “FOR RESEARCH USE ONLY.”

: How should I store hexarelin upon receipt?
A: Hexarelin should be stored at -20°C (freezer) immediately upon receipt, protected from light and moisture. Lyophilized powder is stable when stored properly. Avoid repeated freeze-thaw cycles.

: What solvent should I use for reconstitution?
A: For most research applications, sterile water, PBS (pH 7.4), or cell culture medium is appropriate. Hexarelin is soluble in aqueous buffers. Contact our technical team for application-specific recommendations.  hexarelin peptide for sale

: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.

: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements.

: What documentation do you provide for research compliance?
A: Every order includes batch-specific Certificates of Analysis (COAs) with HPLC and MS data. We also provide commercial invoices, packing lists, and customs documentation as needed.


Quality Control: The Apeptide Standard

Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards.  hexarelin peptide for sale

Analytical Methods

  • HPLC Analysis: Every batch tested for purity (typically 99%+)

  • Mass Spectrometry: ESI-MS for molecular weight confirmation (887.04 Da expected)

  • Amino Acid Analysis: Sequence verification including D-amino acids

  • Chiral Analysis: Confirmation of correct D- and L-amino acid configurations

  • C-Terminal Amidation Confirmation: Essential for biological activity

  • Peptide Content Determination: Accurate net peptide weight (≥80% typical)

  • Counterion Analysis: Acetate content specified

  • Water Content: ≤8.0% by Karl Fischer

  • Endotoxin Testing: <0.05 EU/mg available for cell culture applications

  • Stability Studies: Ensuring integrity under various conditions

Batch Documentation

Each shipment includes:

  • Certificate of Analysis with actual test results

  • HPLC chromatogram (available upon request)

  • Mass spectrometry data

  • Chiral purity confirmation

  • Batch number for traceability

  • Expiration date and storage recommendations

  • Reconstitution guidelines


Beyond Hexarelin: A Complete Research Partner

Apeptide (Shanghai) Co., Ltd. is more than just a supplier of hexarelin peptide for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide.

Our Capabilities

  • Custom Synthesis: Develop proprietary peptides for your specific research needs

  • Catalog Peptides: Hundreds of sequences available for immediate shipment

  • Growth Hormone Secretagogue Library: Including hexarelin, GHRP-2, GHRP-6, ipamorelin, and analogs

  • Fluorescent Dyes: High-purity labeling agents for imaging and detection

  • Amino Acids: Building blocks for synthesis and research

Quality Certifications & Compliance

  • Licensed manufacturer with physical facility in Pudong District, Shanghai

  • Rigorous quality control protocols

  • Transparent documentation and traceability

  • Experienced technical support team

  • Strict adherence to research-use-only compliance


The Science Behind Hexarelin: A Potent GH Secretagogue with Cardioprotective Properties

Hexarelin was developed as part of a systematic effort to create potent and selective growth hormone secretagogues . Its structure includes D-amino acids (D-2-Methyl-Trp, D-Phe) that confer resistance to enzymatic degradation while maintaining high affinity for the GHS-R1a receptor . hexarelin peptide for sale

The peptide’s unique properties include:

  • Extreme potency: EC₅₀ in the low nanomolar range, comparable to ghrelin

  • Dual mechanism: Direct pituitary action and hypothalamic GHRH stimulation

  • Synergistic effects: Amplifies GH release when combined with GHRH

  • Cardioprotective effects: Direct cardiac effects independent of GH release

Key research findings include:

  • Cardioprotection: Hexarelin reduces infarct size in ischemia-reperfusion models through GHS-R1a activation on cardiomyocytes

  • Endothelial function: Improves endothelial function and reduces vascular inflammation

  • Cardiac contractility: Enhances myocardial contractility in isolated heart preparations

  • No appetite stimulation: Unlike ghrelin, hexarelin does not significantly stimulate food intake

These properties make hexarelin a valuable research tool not only for GH axis studies but also for cardiovascular research investigating the non-ghrelin functions of the GHS-R1a receptor .  hexarelin peptide for sale

The search for premium “hexarelin peptide for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of peptides and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest research materials available. Whether you need hexarelin for growth hormone research, receptor pharmacology, cardiovascular studies, or specialized endocrine applications, we are your trusted manufacturing partner.

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All compounds are lab-tested for 99%+ purity and sold strictly for research and laboratory use only. Whether you need small orders or wholesale peptides, we deliver quality you can count on. Shandong Yixin Peptides 📍 No. 9 Lu Shan Road, Dong Cheng Street, Shandong, China 📍 Florida City, FL, USA 📧 Email: support@shandongyixinpeptides.com 📞 Phone: +1 (214) 380-4414 🕒 Hours: Mon – Sat | 9:00 AM – 6:00 PM
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