5-Amino-1MQ

Premium 5-Amino-1MQ Peptide for Sale – Direct from Shanghai Manufacturer

5-Amino-1MQ represents a breakthrough in metabolic research, targeting a key enzyme at the intersection of cellular metabolism, energy regulation, and aging. As a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT), this innovative small molecule offers researchers a powerful tool for investigating metabolic pathways, adipose tissue biology, and age-related metabolic decline . If you are searching for “5-Amino-1MQ peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the significance of this novel NNMT inhibitor and can deliver the purity your studies demand. That partner is Apeptide (Shanghai) Co., Ltd.

We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, small molecule inhibitors, catalog peptides, fluorescent dyes, and amino acids. When you purchase 5-Amino-1MQ peptide for sale from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller.

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Understanding 5-Amino-1MQ: The NNMT Inhibitor Revolution

5-Amino-1MQ is a small molecule inhibitor specifically designed to target nicotinamide N-methyltransferase (NNMT), an enzyme that plays a critical role in cellular metabolism by methylating nicotinamide using S-adenosylmethionine (SAM) as a methyl donor . NNMT is a metabolic switch that regulates energy balance, and its inhibition has emerged as a promising research avenue for metabolic disorders.

Key Characteristics

• Chemical Name: 5-Amino-1-methylquinolinium iodide (5-amino-1-methylquinolin-1-ium iodide)

• Molecular Formula: C₁₀H₁₁N₂•I

• Molecular Weight: Approximately 286.11 g/mol

• CAS Number: 2805931-03-5

• Form: Lyophilized powder

• Purity: ≥99% (verified by HPLC)

• Storage: -20°C, protected from light and moisture, under inert atmosphere

Mechanism of Action

5-Amino-1MQ exerts its effects through selective inhibition of NNMT:

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Why 5-Amino-1MQ Matters in Research

5-Amino-1MQ has emerged as a critical research tool following discoveries that NNMT is a key regulator of cellular metabolism in adipose tissue, liver, and muscle. Elevated NNMT expression is associated with obesity, insulin resistance, and metabolic dysfunction .

Key Research Applications

Scientists seek 5-Amino-1MQ peptide for sale for various laboratory investigations:

Key Research Insights

• NNMT as a Metabolic Switch: NNMT acts as a metabolic brake, consuming methyl groups and reducing NAD⁺ availability. Its inhibition releases this brake, promoting energy expenditure

• Adipose Tissue Specificity: NNMT is highly expressed in adipose tissue of obese individuals, making it a promising target for obesity research

• NAD⁺ Connection: By preserving NAD⁺, NNMT inhibition supports sirtuin activity, linking it to longevity and metabolic health

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The Critical Importance of Quality for 5-Amino-1MQ Research

When you purchase 5-Amino-1MQ peptide for sale, quality parameters are non-negotiable. This small molecule inhibitor requires precise synthesis to ensure correct structure, stereochemistry, and purity for reliable research results.

The Apeptide Quality Standard

• 99% Purity Guarantee: Verified by High-Performance Liquid Chromatography (HPLC)

• Mass Spectrometry: Molecular weight confirmation (286.11 g/mol expected)

• NMR Analysis: Structural confirmation (available upon request)

• Elemental Analysis: Composition verification

• Counterion Analysis: Iodide content specified

• Residual Solvents: Meets ICH guidelines

• Water Content: ≤0.5% by Karl Fischer

• Endotoxin Testing: Available for cell culture applications

• Batch-Specific COAs: Full traceability with Certificates of Analysis

• Stability Testing: Ensuring integrity from our lab to yours

Why Purity Matters for 5-Amino-1MQ Research

• Enzyme Inhibition Studies: IC₅₀ values require precise dosing and pure compound

• Cell-Based Assays: Impurities can confound metabolic measurements

• In Vivo Studies: Dosing consistency critical for metabolic research

• Mechanistic Studies: Pathway analysis demands documented purity

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The Manufacturer Advantage: Why Source 5-Amino-1MQ from Apeptide

When you search for “5-Amino-1MQ peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice.

Complete Transparency

• Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.

• Manufacturing Expertise: Decades of combined experience in small molecule synthesis and biochemical production.

• No Middlemen: You pay manufacturer-direct pricing, not reseller markups.

Technical Expertise

Our team understands the specific requirements for 5-Amino-1MQ research:

• Proper handling to maintain compound stability (light-sensitive)

• Appropriate reconstitution for various assay systems

• Storage conditions to prevent degradation (inert atmosphere recommended)

• Documentation requirements for research compliance

• Understanding of NNMT inhibition mechanisms

Quality You Can Trust

• Rigorous Testing: Every batch undergoes HPLC and MS analysis

• Documentation: Full COAs provided for complete traceability

• Consistency: Reliable quality batch after batch

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Seamless Supply to the USA Market

Sourcing 5-Amino-1MQ peptide for sale from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners.

• Fast Shipping: 5-7 business days to US addresses

• Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive compounds

• Light Protection: Amber vials to prevent photodegradation

• Desiccant Protection: Double-sealed packaging to prevent moisture absorption

• Inert Atmosphere: Available upon request for oxygen-sensitive applications

• Wholesale Programs: Dedicated support for small and large supply companies

• Customs Expertise: Smooth clearance with complete documentation

• Tracking Integration: Real-time visibility from Shanghai to your lab

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Research Applications: Where 5-Amino-1MQ Excels

Understanding the diverse applications of 5-Amino-1MQ helps researchers appreciate why quality matters.

Metabolic Research

• NNMT inhibition in adipocyte models

• Energy expenditure and thermogenesis studies

• Glucose homeostasis and insulin sensitivity

• Adipose tissue browning investigations

Obesity Research

• Diet-induced obesity (DIO) models

• Adipocyte size and fat mass studies

• Metabolic rate and caloric expenditure

• Weight regulation mechanisms

Diabetes Research

• Glucose tolerance tests (GTT)

• Insulin sensitivity assays

• Pancreatic beta cell function

• Peripheral glucose uptake studies

Aging Research

• Age-related metabolic decline

• NAD⁺ metabolism and sirtuin activation

• Mitochondrial function in aging

• Age-associated weight gain

Cancer Metabolism

• NNMT overexpression in tumor models

• Cancer cell proliferation studies

• Metabolic reprogramming in cancer

• Drug combination investigations

Liver Metabolism

• Non-alcoholic fatty liver disease (NAFLD) models

• Hepatic lipid accumulation

• Steatosis and fibrosis studies

• Liver function and metabolic health

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Frequently Asked Questions

: What exactly is 5-Amino-1MQ peptide for sale at Apeptide?
A: 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small molecule inhibitor that selectively targets nicotinamide N-methyltransferase (NNMT), a key enzyme in cellular metabolism. It is supplied strictly for laboratory investigation and in vitro research only, not for human consumption. Our 5-Amino-1MQ is manufactured at our Shanghai facility with 99% purity verification.

: What purity levels do you guarantee for 5-Amino-1MQ?
A: We guarantee 99% purity, verified by HPLC testing with Certificates of Analysis available for every batch. Each COA provides detailed purity analysis, mass spectrometry confirmation (286.11 g/mol expected), and batch-specific data.

: What is the CAS number for 5-Amino-1MQ?
A: The CAS number for 5-Amino-1MQ is 2805931-03-5 .

: What is the molecular weight of 5-Amino-1MQ?
A: The molecular weight is approximately 286.11 g/mol .

: How does 5-Amino-1MQ work in research models?
A: 5-Amino-1MQ selectively inhibits nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide using SAM. By inhibiting NNMT, it preserves NAD⁺ levels and prevents depletion of methyl donors, leading to increased energy expenditure and improved metabolic function .

: What is NNMT and why is it important in research?
A: Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that regulates energy balance by consuming methyl groups and reducing NAD⁺ availability. Elevated NNMT expression is associated with obesity, insulin resistance, and metabolic dysfunction, making it a promising research target .

: Is your 5-Amino-1MQ for human consumption?
A: Absolutely not. Our 5-Amino-1MQ is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. All products are labeled “FOR RESEARCH USE ONLY.”

: How should I store 5-Amino-1MQ upon receipt?
A: 5-Amino-1MQ should be stored at -20°C (freezer) immediately upon receipt, protected from light and moisture. It is light-sensitive and should be stored in amber vials or protected from direct light. Under inert atmosphere (argon/nitrogen) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.

: What solvent should I use for reconstitution?
A: For most research applications, DMSO is the recommended solvent for stock solutions. For cell culture applications, dilute in PBS or culture medium after initial DMSO dissolution. Contact our technical team for application-specific recommendations.

: What is the IC₅₀ of 5-Amino-1MQ for NNMT inhibition?
A: 5-Amino-1MQ is a potent NNMT inhibitor with activity in the low micromolar to sub-micromolar range. Exact IC₅₀ values depend on assay conditions. Please contact our technical team for specific assay data.

: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.

: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements.

: What documentation do you provide for research compliance?
A: Every order includes batch-specific Certificates of Analysis (COAs) with HPLC and MS data. We also provide commercial invoices, packing lists, and customs documentation as needed.

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Quality Control: The Apeptide Standard

Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards.

Analytical Methods

• HPLC Analysis: Every batch tested for purity (typically 99%+)

• Mass Spectrometry: ESI-MS or MALDI-TOF for molecular weight confirmation (286.11 Da expected)

• NMR Analysis: Structural confirmation (¹H-NMR, ¹³C-NMR available upon request)

• Elemental Analysis: Composition verification

• Counterion Analysis: Iodide content specified

• Residual Solvents: Acetonitrile ≤0.041%, Methanol ≤0.3% per ICH Q3C

• Water Content: ≤0.5% by Karl Fischer

• Heavy Metals: ≤10 ppm

• Endotoxin Testing: <0.05 EU/mg available for cell culture applications

Batch Documentation

Each shipment includes:

• Certificate of Analysis with actual test results

• HPLC chromatogram (available upon request)

• Mass spectrometry data

• Batch number for traceability

• Expiration date and storage recommendations

• Reconstitution guidelines

• Safety Data Sheet (SDS)

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Beyond 5-Amino-1MQ: A Complete Research Partner

Apeptide (Shanghai) Co., Ltd. is more than just a supplier of 5-Amino-1MQ peptide for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide.

Our Capabilities

• Custom Synthesis: Develop proprietary small molecule inhibitors and peptides for your specific research needs

• Catalog Peptides: Hundreds of sequences available for immediate shipment

• Metabolic Research Tools: Including NNMT inhibitors, sirtuin activators, and NAD⁺ modulators

• Fluorescent Dyes: High-purity labeling agents for imaging and detection

• Amino Acids: Building blocks for synthesis and research

 Certifications and Compliance

• Licensed manufacturer with physical facility in Pudong District, Shanghai

• Rigorous quality control protocols

• Transparent documentation and traceability

• Experienced technical support team

• Strict adherence to research-use-only compliance

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The Science Behind 5-Amino-1MQ and NNMT Inhibition

The discovery that NNMT is a critical regulator of cellular metabolism has opened new avenues for metabolic research. NNMT methylates nicotinamide using S-adenosylmethionine (SAM) as a methyl donor, producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH) . This reaction consumes methyl groups and reduces NAD⁺ availability, as nicotinamide is a precursor for NAD⁺ biosynthesis .

In adipose tissue of obese individuals, NNMT expression is significantly elevated, creating a metabolic brake that reduces energy expenditure and promotes fat storage . By inhibiting NNMT, 5-Amino-1MQ releases this brake, leading to increased energy expenditure, improved glucose homeostasis, and reduced adiposity .

The compound’s selectivity for NNMT over other methyltransferases makes it a valuable research tool for dissecting the specific role of NNMT in metabolism. Its small molecule structure enables cell permeability, allowing both in vitro and in vivo applications .

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The search for premium “5-Amino-1MQ peptide for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of research compounds and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest materials available. Whether you need 5-Amino-1MQ for metabolic research, obesity studies, diabetes investigations, or specialized NNMT inhibition research, we are your trusted manufacturing partner.