CJC-1295 Without DAC 5mg + IPA 5mg Peptide Blend – Direct from Shanghai Manufacturer
The combination of CJC-1295 without DAC and Ipamorelin (IPA) represents one of the most sophisticated approaches to growth hormone research, offering scientists a powerful synergistic tool for investigating the GH axis . This dual-peptide blend combines a growth hormone-releasing hormone (GHRH) analog with a growth hormone secretagogue (GHS), creating a complementary mechanism that amplifies endogenous GH secretion while preserving physiological pulsatility and feedback mechanisms . If you are searching for “CJC-1295 with Ipamorelin blend for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of both peptides and can deliver the purity your studies demand. That partner is Apeptide (Shanghai) Co., Ltd. CJC-1295 with Ipamorelin blend for sale
We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase our CJC-1295 without DAC 5mg + IPA 5mg peptide blend from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller.
Understanding the Synergistic GHRH/GHRP Combination
The combination of CJC-1295 without DAC (a GHRH analog) and Ipamorelin (a GHRP) targets the growth hormone axis through two distinct but complementary pathways, creating a synergistic amplification of GH release . CJC-1295 with Ipamorelin blend for sale
Component 1: CJC-1295 Without DAC
CJC-1295 without DAC is a synthetic 30-amino acid analog of growth hormone-releasing hormone (GHRH) that stimulates GH release by activating GHRH receptors on pituitary somatotrophs . Its short half-life (~30 minutes) produces pulsatile GH release that mimics natural secretion.
Component 2: Ipamorelin (IPA)
Ipamorelin is a synthetic pentapeptide that acts as a highly selective growth hormone secretagogue (GHS) by activating the ghrelin receptor (GHS-R1a) . It is known for its selectivity—stimulating GH release without significant effects on prolactin, ACTH, cortisol, or appetite.
The Synergistic Mechanism
| Component | Receptor Target | Primary Action | Complementary Effect |
|---|---|---|---|
| CJC-1295 (GHRH Analog) | GHRH Receptor (GHRHR) | Stimulates GH synthesis and release | Direct pituitary action |
| Ipamorelin (GHRP) | Ghrelin Receptor (GHS-R1a) | Amplifies GH release; synergistic with GHRH | Pituitary + hypothalamic action |
| Synergistic Combination | Both pathways | 3-10x amplification of GH release | Preserves pulsatility; reduces desensitization |
How Synergy Works
When combined, CJC-1295 and Ipamorelin work through complementary mechanisms:
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CJC-1295 activates GHRH receptors, stimulating GH synthesis and release
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Ipamorelin activates GHS-R1a, further amplifying GH release and potentiating the GHRH signal
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Combined effect produces significantly greater GH release than either peptide alone, while preserving physiological pulsatility
Product Specifications
| Parameter | Specification |
|---|---|
| CJC-1295 Without DAC | 5 mg |
| Ipamorelin (IPA) | 5 mg |
| Total Peptide Content | 10 mg |
| CJC-1295 Sequence | Modified 30-aa GHRH analog |
| Ipamorelin Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| CJC-1295 MW | ~3,367.9 g/mol |
| Ipamorelin MW | ~711.86 g/mol |
| Purity | ≥99% (verified by HPLC) |
| Form | Lyophilized powder (pre-mixed or separate vials) |
| Storage | -20°C, protected from light and moisture |
Why This Combination Matters in Research
The CJC-1295 + Ipamorelin combination has become a standard tool in growth hormone research due to its ability to produce robust, pulsatile GH release while preserving normal feedback mechanisms .
Key Research Applications
| Research Area | Key Findings | Research Context |
|---|---|---|
| Growth Hormone Research | Synergistic GH release (3-10x amplification); preserves pulsatility | Endocrinology, pituitary function |
| Pulsatile GH Studies | Mimics natural GH pulsatility; preserves feedback mechanisms | Endocrine physiology, GH regulation |
| Aging Research | Counteracts age-related GH decline (somatopause) | Gerontology, age-related metabolic changes |
| Metabolic Research | Influences lipid metabolism, body composition, insulin sensitivity | Obesity, metabolic regulation |
| Receptor Pharmacology | Dual pathway activation (GHRHR + GHS-R1a) | Receptor binding, signal transduction |
| Comparative Studies | Selective GHRP vs. other GHS compounds | Endocrinology, drug development |
Key Research Insights
| Finding | Significance |
|---|---|
| Synergistic Amplification | Combined stimulation produces 3-10x greater GH release than either peptide alone |
| Preserved Pulsatility | Short half-lives maintain natural pulsatile secretion patterns |
| No Desensitization | Preserves receptor sensitivity and feedback mechanisms |
| Ipamorelin Selectivity | Minimal effects on prolactin, ACTH, cortisol, or appetite |
The Critical Importance of Quality for Peptide Blends
When you purchase a CJC-1295 with Ipamorelin blend for sale, quality parameters are non-negotiable. Both peptides require precise synthesis, and accurate dosing of each component is essential for reproducible research.
The Apeptide Quality Standard
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99% Purity Guarantee: Verified by HPLC for each component
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Mass Spectrometry: Molecular weight confirmation for both peptides
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Amino Acid Analysis: Sequence verification
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C-Terminal Amidation Confirmation: Essential for both peptides
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Chiral Purity: Confirmation of D-amino acid configurations in ipamorelin
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Peptide Content Determination: Accurate net peptide weight (≥80% typical)
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Counterion Analysis: Acetate content specified
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Water Content: ≤8.0% by Karl Fischer
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Endotoxin Testing: <0.05 EU/mg available for cell culture applications
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Batch-Specific COAs: Full traceability with Certificates of Analysis
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Stability Testing: Ensuring integrity from our lab to yours
Why Purity Matters for This Blend
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Synergistic Studies: Accurate dosing of both components is essential
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Receptor Binding: EC₅₀ values in nanomolar range require precise dosing
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In Vivo Studies: Dosing consistency critical for GH and IGF-1 measurements
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Mechanistic Studies: Pathway analysis demands documented purity
The Manufacturer Advantage: Why Source This Blend from Apeptide
When you search for “CJC-1295 with Ipamorelin blend for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice.
Complete Transparency
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Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.
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Manufacturing Expertise: Decades of combined experience in peptide synthesis including D-amino acids and modified sequences.
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No Middlemen: You pay manufacturer-direct pricing, not reseller markups.
Technical Expertise
Our team understands the specific requirements for this blend:
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Importance of synergistic GHRH/GHRP mechanisms
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Proper handling to maintain peptide stability
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Appropriate reconstitution for both components
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Storage conditions to prevent degradation
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Documentation requirements for research compliance
Quality You Can Trust
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Rigorous Testing: Every batch undergoes HPLC and MS analysis
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Documentation: Full COAs provided for complete traceability
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Consistency: Reliable quality batch after batch
Seamless Supply to the USA Market
Sourcing this peptide blend from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners.
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Fast Shipping: 5-7 business days to US addresses
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Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive peptides
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Desiccant Protection: Double-sealed packaging to prevent moisture absorption
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Wholesale Programs: Dedicated support for small and large supply companies
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Customs Expertise: Smooth clearance with complete documentation
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Tracking Integration: Real-time visibility from Shanghai to your lab
Research Applications: Where This Blend Excels
Understanding the diverse applications of this GHRH/GHRP combination helps researchers appreciate why quality matters.
Endocrinology Research
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GH pulsatility and regulation studies
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Pituitary somatotroph function
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GHRH and GHS-R1a receptor pharmacology
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Synergistic signaling mechanisms
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Feedback loop investigations (IGF-1, somatostatin)
Pulsatile GH Studies
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Physiological GH release modeling
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Pulsatility and metabolic effects
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Frequency and amplitude analysis
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Circadian rhythm interactions
Metabolic Research
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GH/IGF-1 axis and energy homeostasis
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Lipid metabolism and body composition
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Insulin sensitivity and glucose regulation
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Adipose tissue biology
Aging Research
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Somatopause models
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Age-related GH decline
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Frailty and sarcopenia studies
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Bone metabolism and osteoporosis
Receptor Pharmacology
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Dual pathway activation studies
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GHRHR and GHS-R1a crosstalk
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Biased agonism investigations
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Comparative GHRP studies
Frequently Asked Questions
: What exactly is the CJC-1295 without DAC 5mg + IPA 5mg peptide blend for sale at Apeptide?
A: This is a research-grade combination containing CJC-1295 without DAC (5 mg) and Ipamorelin (5 mg). CJC-1295 is a GHRH analog that stimulates GH release. Ipamorelin is a selective GHRP that amplifies GH release. Together, they produce synergistic GH stimulation. It is supplied strictly for laboratory investigation and in vitro research only, not for human consumption. CJC-1295 with Ipamorelin blend for sale
: What purity levels do you guarantee for this blend?
A: We guarantee 99% purity for both CJC-1295 and Ipamorelin, verified by HPLC testing with Certificates of Analysis available for every batch.
: What is the CAS number for these peptides?
A: CJC-1295 CAS: 863288-34-0 . Ipamorelin CAS: 170851-70-4 .
: How does this combination produce synergistic effects?
A: CJC-1295 activates GHRH receptors on pituitary somatotrophs. Ipamorelin activates ghrelin receptors (GHS-R1a). Together, they produce 3-10x greater GH release than either peptide alone, while preserving physiological pulsatility .
: What is the difference between CJC-1295 with DAC and without DAC?
A: CJC-1295 with DAC contains a Drug Affinity Complex that extends half-life to 5-8 days, producing sustained GH release. Without DAC, the peptide has a short half-life (~30 minutes), producing pulsatile GH release that mimics natural secretion . CJC-1295 with Ipamorelin blend for sale
: Why is Ipamorelin preferred over other GHRPs?
A: Ipamorelin is highly selective for GH release, with minimal effects on prolactin, ACTH, cortisol, or appetite—unlike GHRP-6 and GHRP-2 .
: Is your blend for human consumption?
A: Absolutely not. This peptide blend is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. All products are labeled “FOR RESEARCH USE ONLY.”
: How should I store this blend upon receipt?
A: Store at -20°C (freezer) immediately upon receipt, protected from light and moisture. Avoid repeated freeze-thaw cycles.
: What solvent should I use for reconstitution?
A: For most research applications, sterile water, PBS (pH 7.4), or cell culture medium is appropriate. Both peptides are soluble in aqueous buffers. Contact our technical team for application-specific recommendations.
: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.
: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements. CJC-1295 with Ipamorelin blend for sale
Quality Control: The Apeptide Standard
Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards.
Analytical Methods
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HPLC Analysis: Every batch tested for purity (typically 99%+)
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Mass Spectrometry: ESI-MS for molecular weight confirmation
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Amino Acid Analysis: Sequence verification for both peptides
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C-Terminal Amidation Confirmation: Essential for activity
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Chiral Analysis: Confirmation of D-amino acid configurations (ipamorelin)
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Peptide Content Determination: Accurate net peptide weight
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Endotoxin Testing: <0.05 EU/mg available
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Stability Studies: Ensuring integrity under various conditions
Batch Documentation
Each shipment includes:
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Certificate of Analysis for CJC-1295 with actual test results
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Certificate of Analysis for Ipamorelin with actual test results
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Batch number for traceability
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Expiration date and storage recommendations
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Reconstitution guidelines
Beyond the Blend: A Complete Research Partner
Apeptide (Shanghai) Co., Ltd. is more than just a supplier of CJC-1295 with Ipamorelin blend for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide. CJC-1295 with Ipamorelin blend for sale
Our Capabilities
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Custom Synthesis: Develop proprietary peptides and blends for your specific research needs
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Catalog Peptides: Hundreds of sequences available for immediate shipment
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Growth Hormone Research Library: Including GHRH analogs, GHRPs, and combination blends
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Fluorescent Dyes: High-purity labeling agents for imaging and detection
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Amino Acids: Building blocks for synthesis and research
Quality Certifications & Compliance
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Licensed manufacturer with physical facility in Pudong District, Shanghai
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Rigorous quality control protocols
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Transparent documentation and traceability
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Experienced technical support team
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Strict adherence to research-use-only compliance
The Science Behind GHRH/GHRP Synergy
The synergistic effect of combining a GHRH analog with a GHRP is well-documented in endocrinology literature . GHRH acts directly on pituitary somatotrophs to stimulate GH synthesis and release via the cAMP pathway . GHRPs (such as ipamorelin) activate the ghrelin receptor (GHS-R1a) on both pituitary and hypothalamic neurons, amplifying GH release through the phospholipase C pathway . CJC-1295 with Ipamorelin blend for sale
When both pathways are activated simultaneously:
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Intracellular calcium is increased via both cAMP and PLC pathways
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GH synthesis is upregulated through multiple signaling cascades
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Somatostatin inhibition is overcome, allowing maximal GH release
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Pulsatile secretion is maintained, preserving physiological feedback
The result is a 3-10 fold amplification of GH release compared to either agent alone, making this combination a powerful research tool for studying GH axis physiology .
The search for premium “CJC-1295 with Ipamorelin blend for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of peptides and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest research materials available. Our CJC-1295 without DAC 5mg + IPA 5mg peptide blend offers researchers a convenient, precisely formulated combination of two synergistic GH-releasing peptides, enabling investigations into the amplified effects of dual pathway activation. CJC-1295 with Ipamorelin blend for sale








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