Survotitude

Premium Survodutide Peptide for Sale – Direct from Shanghai Manufacturer

Survodutide represents a groundbreaking advancement in metabolic research. As a first-in-class dual agonist of the glucagon receptor (GCGR) and glucagon-like peptide-1 receptor (GLP-1R), this 29-amino acid peptide offers researchers a powerful tool for investigating metabolic regulation, energy expenditure, and hepatic function . If you are searching for “survodutide peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this innovative dual agonist and can deliver the purity your studies demand. That partner is Apeptide (Shanghai) Co., Ltd.

We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase survodutide peptide for sale from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller. Survotitude

Understanding Survodutide: The Novel Dual Agonist

Survodutide (CAS: 2805997-46-8) is a synthetic 29-amino acid peptide that functions as a balanced dual agonist of the glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R) . Unlike traditional GLP-1 analogs, this dual mechanism combines the appetite-suppressing effects of GLP-1R activation with the energy-expenditure benefits of GCGR activation .

Key Characteristics

• Sequence: H-{1-amino-1-cyclobutanecarboxylic acid}-QGTFTSDYSKYLDERAAKDFIK-{GGSGSG-γE-C18 di-acid}-WLESA-NH₂

• Molecular Formula: C₁₉₂H₂₈₉N₄₇O₆₁

• Molecular Weight: Approximately 4231.63 g/mol

• CAS Number: 2805997-46-8

• Form: Lyophilized powder

• Purity: ≥99% (verified by HPLC)

• Storage: -20°C, protected from light and moisture

Mechanism of Action

Survodutide exerts its effects through balanced dual receptor activation:

Why Survodutide Matters in Research

Survodutide has been the subject of extensive investigation across multiple research domains, with Phase II clinical trials demonstrating remarkable efficacy in weight reduction and metabolic improvement . The peptide has received Fast Track designation from the FDA and Priority Medicines (PRIME) support from the EMA .    Survotitude

Key Research Applications

Scientists seek survodutide peptide for sale for various laboratory investigations:

Potent In Vitro Activity

• GLP-1R EC₅₀: 0.33 nM in CHO-K1 cells

• GCGR EC₅₀: 0.52 nM in CHO-K1 cells

• Plasma Half-Life: Approximately 6 days, enabling once-weekly dosing

• Albumin Binding: >99% binding to human serum albumin

The Critical Importance of Quality for Survodutide Research

When you purchase survodutide peptide for sale, quality parameters are non-negotiable. Survodutide is a complex 29-amino acid peptide containing a unique N-terminal 1-aminocyclobutane-1-carboxylic acid residue and a C18 di-acid modification for albumin binding . Precise synthesis is essential for correct folding and full biological activity.  Survotitude

The Apeptide Quality Standard

• 99% Purity Guarantee: Verified by High-Performance Liquid Chromatography (HPLC)

• Mass Spectrometry: Molecular weight confirmation (4231.63 Da expected)

• Amino Acid Analysis: Sequence verification of all 29 amino acids

• Peptide Content Determination: Accurate net peptide weight (≥80% typical)

• Counterion Analysis: Acetate content ≤12.0%

• Water Content: ≤8.0% by Karl Fischer

• Endotoxin Testing: ≤50 EU/mg available for cell culture applications

• Batch-Specific COAs: Full traceability with Certificates of Analysis

• Stability Testing: Ensuring integrity from our lab to yours

Why Purity Matters for Survodutide Research

• Dual Receptor Studies: EC₅₀ values in sub-nanomolar range require precise dosing

• In Vivo Studies: Once-weekly dosing demands consistent, pure material

• Mechanistic Studies: Pathway analysis requires documented purity

• Reproducibility: Published research demands batch-to-batch consistency

The Manufacturer Advantage: Why Source Survodutide from Apeptide

When you search for “survodutide peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice.  Survotitude

Complete Transparency

• Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.

• Manufacturing Expertise: Decades of combined experience in peptide synthesis and biochemical production.

• No Middlemen: You pay manufacturer-direct pricing, not reseller markups.  Survotitude

Technical Expertise

Our team understands the specific requirements for survodutide research:

• Proper handling of the C18 di-acid modification for albumin binding

• Appropriate reconstitution for various assay systems

• Storage conditions to prevent degradation (stable for 24 months at -20°C)

• Documentation requirements for research compliance

• Understanding of the balanced dual agonist mechanism

Quality You Can Trust

• Rigorous Testing: Every batch undergoes HPLC and MS analysis

• Documentation: Full COAs provided for complete traceability

• Consistency: Reliable quality batch after batch

Seamless Supply to the USA Market

Sourcing survodutide peptide for sale from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners.

• Fast Shipping: 5-7 business days to US addresses

• Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive peptides

• Desiccant Protection: Double-sealed packaging to prevent moisture absorption

• Wholesale Programs: Dedicated support for small and large supply companies

• Customs Expertise: Smooth clearance with complete documentation

• Discreet Packaging: Professional, temperature-controlled containers

• Tracking Integration: Real-time visibility from Shanghai to your lab

Research Applications: Where Survodutide Excels

Understanding the diverse applications of survodutide helps researchers appreciate why quality matters.  Survotitude

Metabolic Disease Research

• Obesity and weight regulation mechanisms

• Type 2 diabetes pathophysiology

• Glucose homeostasis and insulin sensitivity

• Energy expenditure and metabolic rate studies

Hepatic Research

• Metabolic dysfunction-associated steatohepatitis (MASH) models

• Non-alcoholic fatty liver disease (NAFLD) investigations

• Hepatic steatosis and fibrosis studies

• Liver fat content quantification

Cardiovascular Research

• Cardioprotective mechanisms

• Metabolic syndrome investigations

• Cardiovascular outcome studies (ongoing Phase III trials)

Receptor Pharmacology

• GCGR/GLP-1R dual agonist mechanism studies

• Structure-activity relationship investigations

• Biased agonism and signaling pathway analysis

• Receptor selectivity and potency characterization

Preclinical Model Development

• Diet-induced obesity (DIO) mouse models

• Metabolic dysfunction modeling

• Combination therapy investigations

Frequently Asked Questions

Q: What exactly is survodutide peptide for sale at Apeptide?
A: Survodutide (BI 456906) is a synthetic 29-amino acid peptide that functions as a balanced dual agonist of the glucagon receptor (GCGR) and glucagon-like peptide-1 receptor (GLP-1R) . It is supplied strictly for laboratory investigation and in vitro research only, not for human consumption. Our survodutide is manufactured at our Shanghai facility with 99% purity verification.

Q: What purity levels do you guarantee for survodutide?
A: We guarantee 99% purity, verified by HPLC testing with Certificates of Analysis available for every batch. Each COA provides detailed purity analysis, mass spectrometry confirmation (4231.63 Da expected), and batch-specific data.  Survotitude

Q: What is the CAS number for survodutide?
A: The CAS number for survodutide is 2805997-46-8 .

Q: What is the molecular weight of survodutide?
A: The molecular weight is approximately 4231.63 g/mol .

Q: How does survodutide differ from semaglutide or tirzepatide?
A: While semaglutide is a selective GLP-1R agonist and tirzepatide is a dual GIP/GLP-1R agonist, survodutide is a dual GCGR/GLP-1R agonist. This unique mechanism combines appetite suppression (GLP-1) with increased energy expenditure (glucagon) .

Q: Is your survodutide for human consumption?
A: Absolutely not. Our survodutide is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. Survodutide is an investigational drug in Phase III clinical trials and should only be used in approved clinical settings under proper medical supervision . All products are labeled “FOR RESEARCH USE ONLY.”

Q: How should I store survodutide upon receipt?
A: Survodutide should be stored at -20°C (freezer) immediately upon receipt, protected from light and moisture. Lyophilized powder is stable for up to 24 months when stored properly at -20°C . Avoid repeated freeze-thaw cycles.

Q: What solvent should I use for reconstitution?
A: For most research applications, sterile water, PBS (pH 7.4), or cell culture medium is appropriate. Survodutide is soluble in aqueous buffers. Contact our technical team for application-specific recommendations.

Q: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.

Q: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements.

Q: What documentation do you provide for research compliance?
A: Every order includes batch-specific Certificates of Analysis (COAs) with HPLC and MS data. We also provide commercial invoices, packing lists, and customs documentation as needed.

Q: What clinical trials are currently ongoing for survodutide?
A: Survodutide is currently in Phase III clinical trials for obesity and metabolic dysfunction-associated steatohepatitis (MASH), with multiple Phase II and III studies ongoing worldwide .  Survotitude

Quality Control: The Apeptide Standard

Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards.

Analytical Methods

• HPLC Analysis: Every batch tested for purity (typically 99%+)

• Mass Spectrometry: ESI-MS or MALDI-TOF for molecular weight confirmation (4231.63 Da expected)

• Amino Acid Analysis: Sequence verification of all 29 amino acids

• Peptide Content Determination: Accurate net peptide weight (≥80% typical)

• Counterion Analysis: Acetate content ≤12.0%

• Water Content: ≤8.0% by Karl Fischer

• Endotoxin Testing: ≤50 EU/mg available for cell culture applications

• Stability Studies: Ensuring integrity under various conditions

Batch Documentation

Each shipment includes:

• Certificate of Analysis with actual test results

• HPLC chromatogram (available upon request)

• Mass spectrometry data

• Batch number for traceability

• Expiration date and storage recommendations (24 months at -20°C)

• Reconstitution guidelines

Beyond Survodutide: A Complete Research Partner

Apeptide (Shanghai) Co., Ltd. is more than just a supplier of survodutide peptide for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide.

Our Capabilities

• Custom Synthesis: Develop proprietary peptides for your specific research needs

• Catalog Peptides: Hundreds of sequences available for immediate shipment

• Incretin Peptide Library: Including GLP-1 analogs, dual agonists, and triple agonists

• Fluorescent Dyes: High-purity labeling agents for imaging and detection

• Amino Acids: Building blocks for synthesis and research

Quality Certifications and Compliance

• Licensed manufacturer with physical facility in Pudong District, Shanghai

• Rigorous quality control protocols

• Transparent documentation and traceability

• Experienced technical support team

• Strict adherence to research-use-only compliance

The Science Behind Survodutide

Survodutide’s development represents a significant advancement in metabolic research. Derived from the natural hormone oxyntomodulin (OXM)—a weak dual agonist—survodutide has been structurally optimized to achieve balanced GCGR/GLP-1R activation with a ratio of approximately 1:8 .

The molecular design incorporates a C18 dicarboxylic acid group that binds to albumin, extending the half-life to enable once-weekly subcutaneous administration . The peptide also features a non-coded amino acid (1-aminocyclobutane-1-carboxylic acid) at position 2 to resist proteolytic degradation by dipeptidyl peptidase-4 (DPP-4), and C-terminal amidation for additional stability .

Preclinical studies in diet-induced obese (DIO) mouse models demonstrated that survodutide achieves greater bodyweight-lowering efficacy compared to maximally effective doses of semaglutide . The peptide dose-dependently reduces plasma glucagon and increases energy expenditure, while also reducing acute food intake through GLP-1R-dependent mechanisms .

The search for premium “survodutide peptide for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of peptides and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest research materials available. Whether you need survodutide for metabolic research, obesity studies, MASH investigations, or specialized receptor pharmacology, we are your trusted manufacturing partner.